Blocking a female-only GABA signal that helps glioblastoma evade immunity may boost survival

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory ...
Neuroscience News

GABA Immune Pathway Drives Female Brain Cancer Growth

A new study identifies sex-specific glioblastoma immune mechanism where GABA reprograms granulocytic MDSCs to fuel tumor growth solely in females.
News-Medical.Net

Study uncovers sex-specific immune pathway driving glioblastoma growth

Researchers have identified a critical biological difference in how glioblastoma develops in male and female laboratory ...
Labroots

Specific Immune Pathway Promotes Brain Cancer in Females

Glioblastoma is one of the most common and aggressive brain tumors within adult cancer patients. The cancer cells develop ...
ascopubs.org

Impact of GABA pathway genes expression on first-line treatment outcomes in patients (pts) with metastatic colorectal cancer (mCRC): Data from CALGB/SWOG 80405 (Alliance).

Artemin and immune checkpoint inhibitor (ICI) efficacy in metastatic colorectal cancer (mCRC): A correlative analysis of the Canadian Cancer Trials Group (CCTG) CO.26 trial. This is an ASCO Meeting ...
Nature

GABA Metabolism Disorders and Succinic Semialdehyde Dehydrogenase Deficiency

γ-Aminobutyric acid (GABA) metabolism disorders encompass a spectrum of inherited defects in the enzymes responsible for the synthesis, degradation and recycling of the central nervous system’s ...