Depression is often spoken of as if it were a single condition, a uniform experience of sadness, fatigue, or lack of motivation. However, if we look beyond these experiences, we will understand that ...

Depression is a major global health burden, yet its diagnosis still relies largely on subjective clinical interviews and questionnaires. This review explores how blood-based metabolomics could provide ...

Does a depressive mood inevitably lead to more pessimistic thinking or overanalyzing? A global meta-analysis, the largest of its kind to examine the relationship between a depressive mood and reality ...

People who score high on certain dark triad traits may be better equipped to manage depressive symptoms, according to a new study published in Personality and Individual Differences. The findings ...

Objective Psychological comorbidities are common in adolescents with SLE. Incorporating structured mental-health screening ...

It can be challenging to create a treatment plan for depression. This is especially true for patients who aren't responding to conventional treatments and are undergoing experimental therapies such as ...

Human brain, illustration. Deep brain stimulation can help treat depression, but it can be unclear whether a bout of low mood is a relapse or a bad day. The Conversation — It can be challenging to ...

Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations. Design Umbrella review. Data sources Twelve ...