Oocyte maturation and follicular development are fundamental processes that underpin female fertility. These processes involve the transformation of primordial follicles into a cohort of mature, ...

One characteristic of oocyte development and physiology that has been a mystery for 60 years is the highly present cytoplasmic lattices within the cytoplasm of mammalian oocytes. These were initially ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...