Despite modern high-throughput sequencing, the genetic cause of most rare movement disorders remains unclear. A research team in Bochum and Tübingen has now solved one piece of the puzzle: The ...

Scientists have uncovered a surprising new genetic cause of a rare movement disorder after analyzing nearly 3,000 patients ...

Although spastic quadriplegic cerebral palsy can affect mobility and mental health, your healthcare team is there to support you in finding solutions for your lifestyle. Spastic quadriplegia is a ...

Hereditary spastic paraplegias (HSP) are a group of heterogeneous genetic disorders characterized by the presence of progressive spastic hypertonia and muscle weakness, predominantly affecting the ...

P1 was evaluated at 14 years of age. She is the first-born child to a fourth-degree consanguineous marriage (Fig. S1A). She was born at term with a birth weight of 2.45 Kg (−1 SD). She achieved neck ...

Rare diseases, as the name indicates, only affect a small part of the population. However, for those affected they are particularly challenging, often especially because research into such rare ...

Spastic limb paralysis due to injury to a cerebral hemisphere can cause long-term disability. We investigated the effect of grafting the contralateral C7 nerve from the nonparalyzed side to the ...

Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, is a term used for a group of inherited diseases that affect the upper motor neurons traveling from the brain through ...

Readers, this might be a little premature but I think disabled people could be seeing a turnaround in their public image over the next few months. First of all, our reputation as good-for-nothing ...