Gene-set analysis of GWAS data can best be understood as an analysis using genes as data points, carrying out a test of the relationship between a gene set and the genetic associations of genes with a ...

We surveyed all two-arm phase III RCTs presented at ASCO annual meetings from 1995 to 2003 for which negative results were obtained. Post hoc calculations were performed using a power of 80% and an α ...

The product development lifecycle is long and challenging. Whether it is translational research or clinical research, there are numerous obstacles in the design and management of a study and ...

Power analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required sample size for ...