The benefits of dietary fiber extend beyond digestive health, as dietary fiber-derived metabolites produced by gut microbiota ...

Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells that regulate adaptive immunity, including against cancer. Therefore, understanding the precise activities of ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found in ...

Butyrate, produced when gut bacteria ferment dietary fiber, was shown to influence immune-cell identity, trafficking, and ...

From September 2022 to December 2023, healthy (no infection diagnosed, age 30–50 years, and Rh + blood) male adult donor volunteers at the Pasteur Institute of Iran were carefully chosen following our ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

A type 1 conventional dendritic cell (cDC1), magnified 100 times, that has been supercharged with chimeric antigen receptors to better find and prime anti-tumour immune responses. The project, led by ...

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body’s key cancer-fighters, ...

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation. The study, recently published in PNAS, was conducted over a ...

Treating the brain cancer glioblastoma (GBM) demands more than conventional strategies due to a mix of factors including the cancer’s genetic complexity, invasive growth, and immune resistance. A new ...